Unsupervised sentiment detection with mixtures of Beta-Liouville Multinomial distributions

In this paper, we present a fully Bayesian Beta-Liouville Multinomial mixture model for unsupervised sentiment identification. The Beta-Liouville distribution has recently emerged as a flexible and powerful alternative to the Dirichlet prior in statistical language modeling. While maintaining conjugacy with the Multinomial likelihood, it introduces an additional shape parameter that allows for a more expressive and adaptable covariance structure. For posterior inference, we develop a coordina...

Heart involvements in systemic sclerosis beyond pulmonary hypertension: From conduction, rhythm and function defects to coronary artery disease

Systemic sclerosis (SSc) is a rare systemic disease characterised by progressive fibrosis, vasculopathy, and immune dysregulation, resulting in multiorgan damage. Independently of pulmonary arterial hypertension, cardiac involvement, encompassing myocardial fibrosis, coronary microvascular dysfunction, arrhythmias, conduction disorders, pericardial and valvular disease, and heart failure, represents a frequently underestimated cause of morbidity and mortality. Clinically manifest cardiac dise...

HLA-B*51 Beyond Behcet’s Disease: Topography of Symptoms, Associated Diagnoses, and Characterization of Chronic Inflammatory Arthritis Phenotypes

In the clinical context of the new medical concept of diseases related to the Major Histocompatibility Complex class I (MHC-I-opathy), contrasting data are available on the possible association among HLA-B*51, Behcet’s disease (BD), and spondyloarthritis (SpA). The aim of this retrospective study on a cohort of HLA-B*51-positive patients who were clinically observed for almost 5 years is primarily to evaluate which classification criteria they satisfy among BD, axial (ax) or peripheral (p) Sp...

The Handling and Sampling of Radical Cystectomy Specimens: A Standardized Approach for Pathological Evaluation