Toxoplasma gondii infection in goats in Pakistan: risk factors and public health significance

Background Toxoplasma gondii is an intracellular protozoan parasite infecting warm-blooded animals, including humans. Infection can be associated with fetal mortality and a spectrum of other symptoms. Infection in humans mainly occurs through ingesting undercooked or raw animal products (meat and potentially milk) from infected animals, harbouring cysts or tachyzoites, or water or raw fresh produce contaminated with oocysts shed in feline feces. The South Punjab, Pakistan hosts intensiv...

Chemical migration from conventional and bio-based packaging into fresh-cut produce

Il principio del primato del diritto dell’Unione europea: traiettoria storica e prospettive contemporanee

L’elaborato si propone di ricostruire l’evoluzione storico-giurisprudenziale del principio del primato del diritto UE e analizzare il ruolo che esso riveste nell’ordinamento dell’Unione europea: l’esame della giurisprudenza di Lussemburgo ha costituito il “prisma” attraverso cui valutare le differenti sfumature di un principio oggetto di graduale ma costante rafforzamento. Dall’implicito riconoscimento in Van Gend en Loos e dalla sua espressa “consacrazione” in Costa c. Enel, il primato ...

Immune Signaling and Neurobehavioral Regulation: Dissecting the Roles of Complement Receptors and Regulatory T Cells in Neuroinflammation

Neuroimmune communication is fundamentally important to the regulation of brain function and Behaviours. The current thesis explores the contribution of C3aR and C5aR complement receptors and Tregs to neuroimmune responses and anxiety-like behavior, using genetically modified mice. The primary goals for this work were to investigate the behavioral and inflammatory effects of C3aR-deficiency in response to systemic inflammation induced by lipopolysaccharide (LPS). Characterize the behavioral p...