CINECA IRIS Institutional Research Information System

IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.

Prodotti recenti

Dissecting the IDDCA (Intellectual Developmental Disorder with Cardiac Arrhythmia) syndrome pathogenic mechanisms

La sindrome genetica rara da disabilità intellettiva e disturbo del ritmo cardiaco (acronimo: IDDCA, MIM # 617173) è una malattia multi-sistemica a trasmissione autosomica recessiva con esordio precoce, associata a varianti patogenetiche nel gene GNB5. Il quadro delle manifestazioni cliniche vari...

Development of cryopreservation of human neural tissue as strategy to produce clinical-grade stem cells

The Advanced Therapy Production Unit of the Institute for Stem-cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), headed by prof. Angelo Luigi Vescovi, located in San Giovanni Rotondo (FG – Italy), is a Cell Factory authorized by the competent Ethic Committee to is...

Angiotensin II receptor 1 blockers prolong time to recurrence after radiofrequency ablation in hepatocarcinoma patients.

Keap1/Nrf2 Pathway Profiling: Uncovers Molecular Intersection With Notch Pathway In Small Cell Lung Cancer

Small Cell Lung Cancer (SCLC) represents the most aggressive pulmonary malignancy and accounts for approximately 20% of lung cancers. Despite an initial chemotherapy and radiation response, it recurs rapidly after primary treatment by the development of resistance, with only 6% of patients&#...

Nrf2 Inhibition Is Required To Activate Hepatic Progenitor Cells

The current treatment of liver failure is organ transplantation. Nevertheless, the high costs, lack of donors, treatment-related mortality and long-term immunosuppression make this option possible only for a limited number of patients. Liver stem cell transplantation has been recently proposed as...