IRIS
LASELVA, ONOFRIO
 Distribuzione geografica
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Continente #
EU - Europa 1.030
NA - Nord America 932
AS - Asia 158
SA - Sud America 16
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
Totale 2.138
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Nazione #
US - Stati Uniti d'America 885
IE - Irlanda 509
IT - Italia 164
SE - Svezia 129
UA - Ucraina 114
SG - Singapore 61
CN - Cina 47
CA - Canada 43
FI - Finlandia 38
IN - India 27
DE - Germania 21
GB - Regno Unito 14
BR - Brasile 11
FR - Francia 7
CZ - Repubblica Ceca 6
TR - Turchia 6
BE - Belgio 5
IR - Iran 4
MK - Macedonia 4
MX - Messico 4
NL - Olanda 4
DK - Danimarca 3
CL - Cile 2
EC - Ecuador 2
HK - Hong Kong 2
JP - Giappone 2
PL - Polonia 2
RO - Romania 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AR - Argentina 1
AU - Australia 1
BD - Bangladesh 1
BG - Bulgaria 1
EE - Estonia 1
ES - Italia 1
EU - Europa 1
KR - Corea 1
LU - Lussemburgo 1
LV - Lettonia 1
OM - Oman 1
PK - Pakistan 1
PT - Portogallo 1
RU - Federazione Russa 1
TH - Thailandia 1
VA - Santa Sede (Città del Vaticano) 1
VN - Vietnam 1
Totale 2.138
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Città #
Dublin 509
Chandler 241
Ashburn 95
Nyköping 94
Jacksonville 60
Princeton 46
Singapore 38
Helsinki 32
Wilmington 31
Pune 23
New York 16
Des Moines 14
Milan 14
Redwood City 13
Los Angeles 12
Toronto 11
Bari 9
San Mateo 9
Santa Marinella 8
Cedar Knolls 7
Munich 7
Rome 7
Torino 7
San Severo 6
Seattle 6
Brno 5
Cocoa 5
Espoo 5
Foggia 5
Houghton 5
Shanghai 5
Brussels 4
Guangzhou 4
Leawood 4
San Nicolás de los Garza 4
Skopje 4
Beijing 3
Caserta 3
Catania 3
Chicago 3
Hamilton 3
Kocaeli 3
Moose Jaw 3
Nanjing 3
Norwalk 3
Palermo 3
Paris 3
Santa Clara 3
Turin 3
Vinhedo 3
Angri 2
Aprilia 2
Ardabil 2
Augusta 2
Barletta 2
Benxi 2
Borås 2
Brighton 2
Burnaby 2
Cambridge 2
Castellammare di Stabia 2
Columbia 2
Council Bluffs 2
Delta 2
Derby 2
Dongyang 2
Fasano 2
Iowa City 2
Krakow 2
Lyngby 2
Ottawa 2
Padova 2
Porto Alegre 2
Quito 2
Rockville 2
Serracapriola 2
Stevenage 2
Surrey 2
São Paulo 2
Tampa 2
Taranto 2
Acquaviva delle Fonti 1
Atlanta 1
Atlantic Mine 1
Bangkok 1
Baricella 1
Belmont 1
Billings 1
Boardman 1
Bologna 1
Bordeaux 1
Brindisi 1
Brisbane 1
Broomfield 1
Buenos Aires 1
Cedar Rapids 1
Central 1
Changsha 1
Chengdu 1
Chesterfield 1
Totale 1.488
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Nome #
D1152H MUTATION SHOWS A BICARBONATE BUT NOT A CHLORIDE DEFECT IN PRIMARY NASAL EPITHELIAL CELLS 97
Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells 84
Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization 81
AN ADENOVIRAL VECTOR EXPRESSING CFTR CAN BE USED TO BENCHMARK CFTR MODULATOR RESPONSES IN PATIENT-DERIVED NASAL EPITHELIAL CELLS 55
MODELING CYSTIC FIBROSIS DISEASE AND THERAPIES IN PATIENT DERIVED TISSUES 54
Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator 54
Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation 54
Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis 52
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system 52
The era of CFTR modulators: improvements made and remaining challenges 52
Anti-infectives enhance ORKAMBI rescue of F508del-CFTR function in human bronchial epithelial cells infected with clinical strains of P. aeruginosa 51
Activity of Lumacaftor is not conserved in zebrafish Cftr bearing the major Cystic Fibrosis-causing mutation 51
Photochemically Activated Notch Signaling Hydrogel Preferentially Differentiates Human Derived Hepatoblasts to Cholangiocytes 49
MODULATION OF CFTR BY ITS PHOSPHORYLATION AND INTERACTION WITH SMALL MOLECULES 49
ASSESSING THE NEED FOR CORRECTOR COMBINATIONS FOR MISFOLDED CF VARIANTS OTHER THAN F508DEL 48
Rescue of multiple class II CFTR mutations by elexacaftor+ tezacaftor+ivacaftor mediated in part by the dual activities of Elexacaftor as both corrector and potentiator 48
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers 47
HUMAN IPSCS AND NASAL CELL MODELS FOR CFTR THERATYPING 46
Human Amniotic Mesenchymal Stem Cells and Fibroblasts Accelerate Wound Repair of Cystic Fibrosis Epithelium 44
Allele-specific prevention of nonsense-mediated decay in cystic fibrosis using homology-independent genome editing 44
TRIMETHYLANGELICIN (TMA) BINDS DIRECTLY TO PURIFIED WILD-TYPE CFTR 44
Cholesterol interaction directly enhances intrinsic activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) 44
Insulin-Like Growth Factor Binding Protein (IGFBP-6) as a Novel Regulator of Inflammatory Response in Cystic Fibrosis Airway Cells 43
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers 43
TOWARDS THE DETERMINATION OF THE BINDING SITE OF IVACAFTOR ON CFTR THROUGH USE OF PHOTOAFFINITY LABELING PROBES 43
Modulator Therapy in Cystic Fibrosis Patients with cis Variants in F508del Complex Allele: A Short-Term Observational Case Series 43
Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli) 42
Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site 42
Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains 42
STUDYING THE DISTINCT SENSITIVITIES OF CFTR MODULATORS USING ZEBRAFISH-CFTR 40
A helper-dependent adenoviral vector rescues CFTR to wild type functional levels in CF epithelial cells harbouring class I mutations 39
The CFTR mutation c.3452G>C (D1152H) confers an anion selectivity defect in primary airway tissue that can be rescued by Ivacaftor 37
Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants 36
Human Amniotic Mesenchymal Stem Cells and Fibroblasts AccelerateWound Repair of Cystic Fibrosis Epithelium 35
Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function 35
Trimethylangelicin promotes the functional rescue of F508del CFTR in CF airway cells 35
A protocol for identifying the binding sites of small molecules on the cystic fibrosis transmembrane conductance regulator (CFTR) protein 33
The preclinical discovery and development of the combination of ivacaftor + tezacaftor used to treat cystic fibrosis 33
ORKAMBI/amplifier co-therapy rescues a rare CFTR mutation in gene-edited cells and patient tissue 32
Small-molecule drugs for cystic fibrosis: Where are we now? 32
Lung Disease Management by Iloprost-Loaded Nanoparticles to Address Hyperinflammation Associated with Cystic Fibrosis 31
Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action 31
Insulin-Like Growth Factor Binding Protein (IGFBP-6) as a Novel Regulator of Inflammatory Response in Cystic Fibrosis Airway Cells 29
Induced pluripotent stem cells for cystic fibrosis 29
IGFBP-6 Network in Chronic Inflammatory Airway Diseases and Lung Tumor Progression 28
Orkambi mediated rescue of mucociliary clearance in CF primary respiratory cultures is enhanced by arginine uptake, arginase inhibition and promotion of nitric oxide signalling to the CFTR channel 28
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients 27
The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain 26
Generation of functional ciliated cholangiocytes from human pluripotent stem cells 25
The Oncogenic Theory of Preeclampsia: Is Amniotic Mesenchymal Stem Cells-Derived PLAC1 Involved? 24
Molecular mechanism of action of Trimethylangelicin derivatives as CFTR modulators 24
Preclinical Studies of a Rare CF-Causing Mutation in the Second Nucleotide Binding Domain (c.3700A>G) Show Robust Functional Rescue in Primary Nasal Cultures by Novel CFTR Modulators 24
Phenotyping rare cftr mutations reveal functional expression defects restored by trikaftatm 23
Mucopenetration study of solid lipid nanoparticles containing magneto sensitive iron oxide 23
High-throughput functional analysis of CFTR and other apically localized proteins in iPSC-derived human intestinal organoids 21
One-Step Formation of Protein-Based Tubular Structures for Functional Devices and Tissues 17
Elexacaftor/Tezacaftor/Ivacaftor Accelerates Wound Repair in Cystic Fibrosis Airway Epithelium 16
Olive Leaf Extract (OLE) as a Novel Antioxidant That Ameliorates the Inflammatory Response in Cystic Fibrosis 13
Advances in Preclinical In Vitro Models for the Translation of Precision Medicine for Cystic Fibrosis 5
Editorial: Mechanisms of action of small molecules on CFTR mutants and the impact on cystic fibrosis pathogenesis 4
Totale 2.333
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Categoria #
all - tutte 19.866
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.866
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20206 0 0 0 0 1 0 2 0 1 0 1 1
2020/2021376 55 10 25 3 28 5 33 60 68 38 3 48
2021/2022257 15 12 16 3 22 10 16 26 30 32 7 68
2022/20231.222 101 37 28 83 63 121 27 87 600 22 24 29
2023/2024287 31 16 9 8 13 77 16 57 0 7 13 40
2024/2025158 68 13 22 42 13 0 0 0 0 0 0 0
Totale 2.333