LASELVA, ONOFRIO

LASELVA, ONOFRIO  

Dipartimento di Medicina Clinica e Sperimentale  

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Risultati 1 - 20 di 52 (tempo di esecuzione: 0.034 secondi).
Titolo Data di pubblicazione Autore(i) File
Activity of Lumacaftor is not conserved in zebrafish Cftr bearing the major Cystic Fibrosis-causing mutation 1-gen-2019 Laselva, O.; Erwood, S.; Du, K.; Ivakine, Z.; BEAR C., E
AN ADENOVIRAL VECTOR EXPRESSING CFTR CAN BE USED TO BENCHMARK CFTR MODULATOR RESPONSES IN PATIENT-DERIVED NASAL EPITHELIAL CELLS 1-gen-2019 Ouyang, H.; Cao, H.; Bartlett, C.; Laselva, O.; Gunawardena, T.; Duan, C.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; MORAES T., J
Allele-specific prevention of nonsense-mediated decay in cystic fibrosis using homology-independent genome editing 1-gen-2020 Erwood, S.; Laselva, O.; Bily, T. M. I.; Rutherford, A. H.; BEAR C. E. IVAKINE E., A
Anti-infectives enhance ORKAMBI rescue of F508del-CFTR function in human bronchial epithelial cells infected with clinical strains of P. aeruginosa 1-gen-2020 Laselva, O.; Stone, T. A.; Bear, C. E.; Deber, C. R.
Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells 1-gen-2021 Laselva, Onofrio; Allegretta, Caterina; DI GIOIA, Sante; Avolio, Carlo; Conese, Massimo
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers 1-gen-2022 Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers 1-gen-2022 Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio
Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation 1-gen-2021 Oren, Y. S.; Avizur-Barchad, O.; Ozeri-Galai, E.; Elgrabli, R.; Schirelman, M. R.; Blinder, T.; Stampfer, C. D.; Ordan, M.; Laselva, O.; Cohen-Cymberknoh, M.; Kerem, E.; Bear, C. E.; Kerem, B.
ASSESSING THE NEED FOR CORRECTOR COMBINATIONS FOR MISFOLDED CF VARIANTS OTHER THAN F508DEL 1-gen-2018 Laselva, O.; Bartlett, C.; Popa, A.; Du, K.; Szarics, I; Ouyang, H.; Moraes, T. J.; Gonska, T.; Bear, C. E.
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system 1-gen-2022 Lim, Sang Hyun; Snider, Jamie; Birimberg-Schwartz, Liron; Ip, Wan; Serralha, Joana C; Botelho, Hugo M; Lopes-Pacheco, Miquéias; Pinto, Madalena C; Moutaoufik, Mohamed Taha; Zilocchi, Mara; Laselva, Onofrio; Esmaeili, Mohsen; Kotlyar, Max; Lyakisheva, Anna; Tang, Priscilla; López Vázquez, Lucía; Akula, Indira; Aboualizadeh, Farzaneh; Wong, Victoria; Grozavu, Ingrid; Opacak-Bernardi, Teuta; Yao, Zhong; Mendoza, Meg; Babu, Mohan; Jurisica, Igor; Gonska, Tanja; Bear, Christine E; Amaral, Margarida D; Stagljar, Igor
The CFTR mutation c.3452G>C (D1152H) confers an anion selectivity defect in primary airway tissue that can be rescued by Ivacaftor 1-gen-2020 Laselva, O.; Moraes, T.; He, G.; Bartlett, C.; Szarics, I.; Ouyang, H.; Strug, L.; Bear, C. E.; Gonska, T
Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli) 1-gen-2022 Hossain, MD NIAMAT; De Leo, Vincenzo; Tamborra, Rosanna; Laselva, Onofrio; Ingrosso, Chiara; Daniello, Valeria; Catucci, Lucia; Losito, Ilario; Sollitto, Francesco; Loizzi, Domenico; Conese, Massimo; DI GIOIA, Sante
Cholesterol interaction directly enhances intrinsic activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) 1-gen-2019 Chin, S.; Ramjeesingh, M.; Hung, M.; ERENO-OREBA, J.; Cui, H.; Laselva, O.; Julien, J. -P.; BEAR C., E
Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site 1-gen-2018 Molinski, S.; Shahani, V.; Subramanian, A.; Mackinnon, S.; Woollard, G.; Laforet, M.; Laselva, O.; Morayniss, L.; Bear, C. E.; Windemuth, A
Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization 1-gen-2016 Abbattiscianni, A. C.; Favia, M; Mancini, M. T.; Cardone, R. A.; Guerra, L; Monterisi, S; Castellani, Stefano; Laselva, O; Di Sole, F; Conese, Massimo; Zaccolo, M; Casavola, V.
Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains 1-gen-2018 Laselva, O.; Molinski, S.; Casavola, V.; Bear, C. E.
D1152H MUTATION SHOWS A BICARBONATE BUT NOT A CHLORIDE DEFECT IN PRIMARY NASAL EPITHELIAL CELLS 1-gen-2019 Laselva, O.; Moraes, T. J.; He, G.; Barlett, C.; Szaric, S. OUYANG.; Strug, L.; Bear, C. E.; Gonska, T
Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis 1-gen-2022 Veit, Guido; Silva, Iris; Conese, Massimo; Laselva, Onofrio
Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants 1-gen-2020 Laselva, O.; Bartlett, C.; Popa, A; Ouyang, H.; Gunawardena, T. N. A.; Gonska, T.; Moraes, T. J.; Bear C., E
The era of CFTR modulators: improvements made and remaining challenges 1-gen-2020 Cuevas-Ocaña, Sara; Laselva, Onofrio; Avolio, Julie; Nenna, Raffaella