LASELVA, ONOFRIO
LASELVA, ONOFRIO
Dipartimento di Medicina Clinica e Sperimentale
A helper-dependent adenoviral vector rescues CFTR to wild type functional levels in CF epithelial cells harbouring class I mutations
2020-01-01 Cao, H.; Ouyang, H.; Laselva, O.; Bartlett, C.; Zhou, Z. P. DUAN C.; Gunawardena, T.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; Moraes, T. J.
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients
2021-01-01 Jiang, Jia Xin; Wellhauser, Leigh; Laselva, Onofrio; Utkina, Irina; Bozoky, Zoltan; Gunawardena, Tarini; Ngan, Zoe; Xia, Sunny; Di Paola, Michelle; Eckford, Paul D W; Ratjen, Felix; Moraes, Theo J; Parkinson, John; Wong, Amy P; Bear, Christine E
A protocol for identifying the binding sites of small molecules on the cystic fibrosis transmembrane conductance regulator (CFTR) protein
2022-01-01 Laselva, Onofrio; Petrotchenko, Evgeniy V; Hamilton, C Michael; Qureshi, Zafar; Borchers, Christoph H; Young, Robert N; Bear, Christine E
Activity of Lumacaftor is not conserved in zebrafish Cftr bearing the major Cystic Fibrosis-causing mutation
2019-01-01 Laselva, O.; Erwood, S.; Du, K.; Ivakine, Z.; Bear, C. E.
Allele-specific prevention of nonsense-mediated decay in cystic fibrosis using homology-independent genome editing
2020-01-01 Erwood, S.; Laselva, O.; Bily, T. M. I.; Rutherford, A. H.; BEAR C. E. IVAKINE E., A
AN ADENOVIRAL VECTOR EXPRESSING CFTR CAN BE USED TO BENCHMARK CFTR MODULATOR RESPONSES IN PATIENT-DERIVED NASAL EPITHELIAL CELLS
2019-01-01 Ouyang, H.; Cao, H.; Bartlett, C.; Laselva, O.; Gunawardena, T.; Duan, C.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; MORAES T., J
Anti-infectives enhance ORKAMBI rescue of F508del-CFTR function in human bronchial epithelial cells infected with clinical strains of P. aeruginosa
2020-01-01 Laselva, O.; Stone, T. A.; Bear, C. E.; Deber, C. R.
Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells
2021-01-01 Laselva, Onofrio; Allegretta, Caterina; DI GIOIA, Sante; Avolio, Carlo; Conese, Massimo
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers
2022-01-01 Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio
Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers
2022-01-01 Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio
Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation
2021-01-01 Oren, Y. S.; Avizur-Barchad, O.; Ozeri-Galai, E.; Elgrabli, R.; Schirelman, M. R.; Blinder, T.; Stampfer, C. D.; Ordan, M.; Laselva, O.; Cohen-Cymberknoh, M.; Kerem, E.; Bear, C. E.; Kerem, B.
ASSESSING THE NEED FOR CORRECTOR COMBINATIONS FOR MISFOLDED CF VARIANTS OTHER THAN F508DEL
2018-01-01 Laselva, O.; Bartlett, C.; Popa, A.; Du, K.; Szarics, I; Ouyang, H.; Moraes, T. J.; Gonska, T.; Bear, C. E.
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system
2022-01-01 Lim, Sang Hyun; Snider, Jamie; Birimberg-Schwartz, Liron; Ip, Wan; Serralha, Joana C; Botelho, Hugo M; Lopes-Pacheco, Miquéias; Pinto, Madalena C; Moutaoufik, Mohamed Taha; Zilocchi, Mara; Laselva, Onofrio; Esmaeili, Mohsen; Kotlyar, Max; Lyakisheva, Anna; Tang, Priscilla; López Vázquez, Lucía; Akula, Indira; Aboualizadeh, Farzaneh; Wong, Victoria; Grozavu, Ingrid; Opacak-Bernardi, Teuta; Yao, Zhong; Mendoza, Meg; Babu, Mohan; Jurisica, Igor; Gonska, Tanja; Bear, Christine E; Amaral, Margarida D; Stagljar, Igor
Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli)
2022-01-01 Hossain, MD NIAMAT; De Leo, Vincenzo; Tamborra, Rosanna; Laselva, Onofrio; Ingrosso, Chiara; Daniello, Valeria; Catucci, Lucia; Losito, Ilario; Sollitto, Francesco; Loizzi, Domenico; Conese, Massimo; DI GIOIA, Sante
Cholesterol interaction directly enhances intrinsic activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
2019-01-01 Chin, S.; Ramjeesingh, M.; Hung, M.; ERENO-OREBA, J.; Cui, H.; Laselva, O.; Julien, J. -P.; Bear, C. E.
Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site
2018-01-01 Molinski, S.; Shahani, V.; Subramanian, A.; Mackinnon, S.; Woollard, G.; Laforet, M.; Laselva, O.; Morayniss, L.; Bear, C. E.; Windemuth, A
Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization
2016-01-01 Abbattiscianni, A. C.; Favia, M; Mancini, M. T.; Cardone, R. A.; Guerra, L; Monterisi, S; Castellani, Stefano; Laselva, O; Di Sole, F; Conese, Massimo; Zaccolo, M; Casavola, V.
Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains
2018-01-01 Laselva, O.; Molinski, S.; Casavola, V.; Bear, C. E.
D1152H MUTATION SHOWS A BICARBONATE BUT NOT A CHLORIDE DEFECT IN PRIMARY NASAL EPITHELIAL CELLS
2019-01-01 Laselva, O.; Moraes, T. J.; He, G.; Barlett, C.; Szaric, S. OUYANG.; Strug, L.; Bear, C. E.; Gonska, T
Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis
2022-01-01 Veit, Guido; Silva, Iris; Conese, Massimo; Laselva, Onofrio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A helper-dependent adenoviral vector rescues CFTR to wild type functional levels in CF epithelial cells harbouring class I mutations | 1-gen-2020 | Cao, H.; Ouyang, H.; Laselva, O.; Bartlett, C.; Zhou, Z. P. DUAN C.; Gunawardena, T.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; Moraes, T. J. | |
| A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients | 1-gen-2021 | Jiang, Jia Xin; Wellhauser, Leigh; Laselva, Onofrio; Utkina, Irina; Bozoky, Zoltan; Gunawardena, Tarini; Ngan, Zoe; Xia, Sunny; Di Paola, Michelle; Eckford, Paul D W; Ratjen, Felix; Moraes, Theo J; Parkinson, John; Wong, Amy P; Bear, Christine E | |
| A protocol for identifying the binding sites of small molecules on the cystic fibrosis transmembrane conductance regulator (CFTR) protein | 1-gen-2022 | Laselva, Onofrio; Petrotchenko, Evgeniy V; Hamilton, C Michael; Qureshi, Zafar; Borchers, Christoph H; Young, Robert N; Bear, Christine E | |
| Activity of Lumacaftor is not conserved in zebrafish Cftr bearing the major Cystic Fibrosis-causing mutation | 1-gen-2019 | Laselva, O.; Erwood, S.; Du, K.; Ivakine, Z.; Bear, C. E. | |
| Allele-specific prevention of nonsense-mediated decay in cystic fibrosis using homology-independent genome editing | 1-gen-2020 | Erwood, S.; Laselva, O.; Bily, T. M. I.; Rutherford, A. H.; BEAR C. E. IVAKINE E., A | |
| AN ADENOVIRAL VECTOR EXPRESSING CFTR CAN BE USED TO BENCHMARK CFTR MODULATOR RESPONSES IN PATIENT-DERIVED NASAL EPITHELIAL CELLS | 1-gen-2019 | Ouyang, H.; Cao, H.; Bartlett, C.; Laselva, O.; Gunawardena, T.; Duan, C.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; MORAES T., J | |
| Anti-infectives enhance ORKAMBI rescue of F508del-CFTR function in human bronchial epithelial cells infected with clinical strains of P. aeruginosa | 1-gen-2020 | Laselva, O.; Stone, T. A.; Bear, C. E.; Deber, C. R. | |
| Anti-Inflammatory and Anti-Oxidant Effect of Dimethyl Fumarate in Cystic Fibrosis Bronchial Epithelial Cells | 1-gen-2021 | Laselva, Onofrio; Allegretta, Caterina; DI GIOIA, Sante; Avolio, Carlo; Conese, Massimo | |
| Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers | 1-gen-2022 | Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio | |
| Anticipating New Treatments for Cystic Fibrosis: A Global Survey of Researchers | 1-gen-2022 | Cabral, Bernardo; Terlizzi, Vito; Laselva, Onofrio; Conte Filho, Carlos; Mota, Fabio | |
| Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation | 1-gen-2021 | Oren, Y. S.; Avizur-Barchad, O.; Ozeri-Galai, E.; Elgrabli, R.; Schirelman, M. R.; Blinder, T.; Stampfer, C. D.; Ordan, M.; Laselva, O.; Cohen-Cymberknoh, M.; Kerem, E.; Bear, C. E.; Kerem, B. | |
| ASSESSING THE NEED FOR CORRECTOR COMBINATIONS FOR MISFOLDED CF VARIANTS OTHER THAN F508DEL | 1-gen-2018 | Laselva, O.; Bartlett, C.; Popa, A.; Du, K.; Szarics, I; Ouyang, H.; Moraes, T. J.; Gonska, T.; Bear, C. E. | |
| CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system | 1-gen-2022 | Lim, Sang Hyun; Snider, Jamie; Birimberg-Schwartz, Liron; Ip, Wan; Serralha, Joana C; Botelho, Hugo M; Lopes-Pacheco, Miquéias; Pinto, Madalena C; Moutaoufik, Mohamed Taha; Zilocchi, Mara; Laselva, Onofrio; Esmaeili, Mohsen; Kotlyar, Max; Lyakisheva, Anna; Tang, Priscilla; López Vázquez, Lucía; Akula, Indira; Aboualizadeh, Farzaneh; Wong, Victoria; Grozavu, Ingrid; Opacak-Bernardi, Teuta; Yao, Zhong; Mendoza, Meg; Babu, Mohan; Jurisica, Igor; Gonska, Tanja; Bear, Christine E; Amaral, Margarida D; Stagljar, Igor | |
| Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli) | 1-gen-2022 | Hossain, MD NIAMAT; De Leo, Vincenzo; Tamborra, Rosanna; Laselva, Onofrio; Ingrosso, Chiara; Daniello, Valeria; Catucci, Lucia; Losito, Ilario; Sollitto, Francesco; Loizzi, Domenico; Conese, Massimo; DI GIOIA, Sante | |
| Cholesterol interaction directly enhances intrinsic activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | 1-gen-2019 | Chin, S.; Ramjeesingh, M.; Hung, M.; ERENO-OREBA, J.; Cui, H.; Laselva, O.; Julien, J. -P.; Bear, C. E. | |
| Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site | 1-gen-2018 | Molinski, S.; Shahani, V.; Subramanian, A.; Mackinnon, S.; Woollard, G.; Laforet, M.; Laselva, O.; Morayniss, L.; Bear, C. E.; Windemuth, A | |
| Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization | 1-gen-2016 | Abbattiscianni, A. C.; Favia, M; Mancini, M. T.; Cardone, R. A.; Guerra, L; Monterisi, S; Castellani, Stefano; Laselva, O; Di Sole, F; Conese, Massimo; Zaccolo, M; Casavola, V. | |
| Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains | 1-gen-2018 | Laselva, O.; Molinski, S.; Casavola, V.; Bear, C. E. | |
| D1152H MUTATION SHOWS A BICARBONATE BUT NOT A CHLORIDE DEFECT IN PRIMARY NASAL EPITHELIAL CELLS | 1-gen-2019 | Laselva, O.; Moraes, T. J.; He, G.; Barlett, C.; Szaric, S. OUYANG.; Strug, L.; Bear, C. E.; Gonska, T | |
| Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis | 1-gen-2022 | Veit, Guido; Silva, Iris; Conese, Massimo; Laselva, Onofrio |