An Extensive Literature Search (ELS) by using PubMed, Web of Science and SciFinderfor relevant studies on N-nitroso compounds (NOCs)analysedin foodwas performed.Search queries allowed to obtainatotal number of18592non-redundant references. The relevance analysis of these references was performed by screening of title and abstract related to the chemical identity and characterisation, sources and occurrence in food, toxicokinetics and toxicity ofNOCs applying eligibility criteria.Relevant references accounted for: i)Area 1 (Data on chemical identification and characterisation of NOCs found in food products) 176 documents;ii)Area 2 (Data on sources and occurrence in food, including human milk) 234 documents; Area 3 (Data on toxicokinetics, i.e. absorption, distribution, metabolism, excretion, in experimental animals and humans and from in vitrostudies) 148 documents; Area 4 (Data on toxicity in experimental animals) 143 documents;Area 5 (Data on in silico, in vitroand in vivogenotoxicity and mode of action) 726 documents; Area 6 (Data on observations in humans including epidemiological studies, case reports, biomarkersof exposure)333 documents. A total number of 1494 non-redundant relevant documents was found.
Extensive literature search on N‐nitroso compounds in food
Centonze, Diego;
2022-01-01
Abstract
An Extensive Literature Search (ELS) by using PubMed, Web of Science and SciFinderfor relevant studies on N-nitroso compounds (NOCs)analysedin foodwas performed.Search queries allowed to obtainatotal number of18592non-redundant references. The relevance analysis of these references was performed by screening of title and abstract related to the chemical identity and characterisation, sources and occurrence in food, toxicokinetics and toxicity ofNOCs applying eligibility criteria.Relevant references accounted for: i)Area 1 (Data on chemical identification and characterisation of NOCs found in food products) 176 documents;ii)Area 2 (Data on sources and occurrence in food, including human milk) 234 documents; Area 3 (Data on toxicokinetics, i.e. absorption, distribution, metabolism, excretion, in experimental animals and humans and from in vitrostudies) 148 documents; Area 4 (Data on toxicity in experimental animals) 143 documents;Area 5 (Data on in silico, in vitroand in vivogenotoxicity and mode of action) 726 documents; Area 6 (Data on observations in humans including epidemiological studies, case reports, biomarkersof exposure)333 documents. A total number of 1494 non-redundant relevant documents was found.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
