Functioningadrenocorticaloncocytomaisveryrareneoplasm.Itisusuallynonfunctionalandbenignandincidentallydetected. Generally,thesetumorsoriginateinthekidneys,thyroid,parathyroid,andsalivaryorpituitaryglands;theyhavealsobeenreported inothersitesincludingchoroidplexus,respiratorytract,andlarynx.Histologically,theyarecharacterizedbycellswitheosinophilic granularcytoplasmandnumerouspackedmitochondria.Wereportedacaseofa44-year-oldfemalewhopresentedwithCushing syndrome for hypersecretion of cortisol due to adrenocortical oncocytoma. Magnetic resonance of abdomen revealed a right adrenalmass.Laparoscopicadrenalectomywasperformedandthetumorwaspathologicallyconfirmedasbenignadrenocortical oncocytoma.Aftersurgicaltreatment,Cushing’ssyndrome resolved.

A Rare Case of Functioning Adrenocortical Oncocytoma Presenting as Cushing Syndrome

TARTAGLIA, NICOLA;FERSINI, ALBERTO;AMBROSI, ANTONIO;NERI, VINCENZO
2016-01-01

Abstract

Functioningadrenocorticaloncocytomaisveryrareneoplasm.Itisusuallynonfunctionalandbenignandincidentallydetected. Generally,thesetumorsoriginateinthekidneys,thyroid,parathyroid,andsalivaryorpituitaryglands;theyhavealsobeenreported inothersitesincludingchoroidplexus,respiratorytract,andlarynx.Histologically,theyarecharacterizedbycellswitheosinophilic granularcytoplasmandnumerouspackedmitochondria.Wereportedacaseofa44-year-oldfemalewhopresentedwithCushing syndrome for hypersecretion of cortisol due to adrenocortical oncocytoma. Magnetic resonance of abdomen revealed a right adrenalmass.Laparoscopicadrenalectomywasperformedandthetumorwaspathologicallyconfirmedasbenignadrenocortical oncocytoma.Aftersurgicaltreatment,Cushing’ssyndrome resolved.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11369/335362
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