Obstructive Sleep Apnea (OSAS) is a disease associated with the increase of cardiovascular risk and it is characterized by repeated episodes of Intermittent Hypoxia (IH) which inducing oxidative stress and systemic inflammation. Mitochondria are cell organelles involved in the respiratory that have their own DNA (MtDNA). The aim of this study was to investigate if the increase of oxidative stress in OSAS patients can induce also MtDNA alterations.
Mitochondrial DNA alteration in obstructive sleep apnea
LACEDONIA, DONATO;CARPAGNANO, GIOVANNA ELISIANA;CRISETTI, ELISABETTA;COTUGNO, GRAZIA;PALLADINO, GRAZIA PIA;FOSCHINO BARBARO, MARIA PIA
2015-01-01
Abstract
Obstructive Sleep Apnea (OSAS) is a disease associated with the increase of cardiovascular risk and it is characterized by repeated episodes of Intermittent Hypoxia (IH) which inducing oxidative stress and systemic inflammation. Mitochondria are cell organelles involved in the respiratory that have their own DNA (MtDNA). The aim of this study was to investigate if the increase of oxidative stress in OSAS patients can induce also MtDNA alterations.File in questo prodotto:
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