Oressinergic system: Network between sympathetic system and exercise

Sport, in different ways, change considerably people’s life. The purpose of this experiment was to reveal possible association between the stimulation of sympathetic system induced by exercise and the one induced by the rise of systemic concentration of Orexin A and bring the truth about orexins and sport network. Blood samples were collected from subjects (men, n = 10; age: 23.2 ± 2.11 years) 15, 0 min before the start of exercise, and 30, 45, 60 min after a cycle ergometer exercise at 75 W for 15 min. Also, heart rate (HR), galvanic skin response (GSR), and rectal temperature were monitored. The exercise produce a significant rise (p < 0.01) in plasmatic orexin A with a peak at 30 min after the exercise bout, in association with a rise of the other three monitored variables: HR (p < 0.01), GSR (p < 0.05), and rectal temperature (p < 0.01). Our results indicate that plasmatic orexin A is involved in the reaction to physical activity and in the beneficial effects of sport.