Sfoglia per Autore  LASELVA, ONOFRIO

Opzioni
Mostrati risultati da 1 a 20 di 57
Titolo Data di pubblicazione Autore(i) File
Trimethylangelicin promotes the functional rescue of F508del CFTR in CF airway cells 1-gen-2014 18) FAVIA, M; Mancini, Mt; Bezzerri, V; Guerra, L; Laselva, O; Abbattiscianni, A. C.; Reshkin, Sj; Gambari, R; Cabrini, G; Casavola, V.
TRIMETHYLANGELICIN (TMA) BINDS DIRECTLY TO PURIFIED WILD-TYPE CFTR 1-gen-2015 Laselva, O.; Chin, S; Molinski, S.; Ereno, J; Julien, Jp.; Casavola, V.; Bear, C. E.
Correctors of mutant CFTR enhance subcortical cAMP/PKA signaling via ezrin phosphorylation and cytoskeleton organization 1-gen-2016 Abbattiscianni, A. C.; Favia, M; Mancini, M. T.; Cardone, R. A.; Guerra, L; Monterisi, S; Castellani, Stefano; Laselva, O; Di Sole, F; Conese, Massimo; Zaccolo, M; Casavola, V.
The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain 1-gen-2016 Laselva, O.; Molinski, S.; Casavola, V.; Bear, C. E.
STUDYING THE DISTINCT SENSITIVITIES OF CFTR MODULATORS USING ZEBRAFISH-CFTR 1-gen-2017 Laselva, O.; Bagnat, M.; Bear, C. E.
ORKAMBI/amplifier co-therapy rescues a rare CFTR mutation in gene-edited cells and patient tissue 1-gen-2017 Molinski, S.; Ahmadi, S.; Kulleperuma, K.; Ip, W.; Ouyang, H.; Villella, A.; Miller, J. P.; Lee, P. S.; Kulleperuma, K.; Du, K; DI PAOLA, M.; Eckford, P.; Laselva, O.; Huan, L. J.; Wellhauser, L; Li, E.; Ray, P. N.; Moraes, T. J. GONSKA T.; Ratjen, F; Bear, C. E.
Molecular mechanism of action of Trimethylangelicin derivatives as CFTR modulators 1-gen-2018 Laselva, O.; Marzaro, G.; Vaccarin, C.; Lampronti, I.; Tamanini, A.; Lippi, G.; Gambari, R.; Cabrini, G.; Bear, C. E.; Chilin, A.; Dechecchi, M. C.
MODELING CYSTIC FIBROSIS DISEASE AND THERAPIES IN PATIENT DERIVED TISSUES 1-gen-2018 Xia, S.; Laselva, O.; DI PAOLA, M.; Bartlett, C.; Gonska, T.; Jones, N. L.; Bear, C. E.
HUMAN IPSCS AND NASAL CELL MODELS FOR CFTR THERATYPING 1-gen-2018 Bear, C. E.; Laselva, O.; Gonska, T.; Moraes, T. J.; Eckford, P. D.; Ratjen, F
ASSESSING THE NEED FOR CORRECTOR COMBINATIONS FOR MISFOLDED CF VARIANTS OTHER THAN F508DEL 1-gen-2018 Laselva, O.; Bartlett, C.; Popa, A.; Du, K.; Szarics, I; Ouyang, H.; Moraes, T. J.; Gonska, T.; Bear, C. E.
MODULATION OF CFTR BY ITS PHOSPHORYLATION AND INTERACTION WITH SMALL MOLECULES 1-gen-2018 Bear, C. E.; Hung, M.; Chin, S.; Laselva, O.; Pasyk, S.; Ahmadi, S.; Viirre, R.; Young, R.
Comprehensive mapping of Cystic Fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site 1-gen-2018 Molinski, S.; Shahani, V.; Subramanian, A.; Mackinnon, S.; Woollard, G.; Laforet, M.; Laselva, O.; Morayniss, L.; Bear, C. E.; Windemuth, A
Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains 1-gen-2018 Laselva, O.; Molinski, S.; Casavola, V.; Bear, C. E.
TOWARDS THE DETERMINATION OF THE BINDING SITE OF IVACAFTOR ON CFTR THROUGH USE OF PHOTOAFFINITY LABELING PROBES 1-gen-2019 Hamilton, C.; Laselva, O.; Qureshi, Z.; Hung, M.; Bear, C. E.; Young, R. N.
Cholesterol interaction directly enhances intrinsic activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) 1-gen-2019 Chin, S.; Ramjeesingh, M.; Hung, M.; ERENO-OREBA, J.; Cui, H.; Laselva, O.; Julien, J. -P.; Bear, C. E.
Activity of Lumacaftor is not conserved in zebrafish Cftr bearing the major Cystic Fibrosis-causing mutation 1-gen-2019 Laselva, O.; Erwood, S.; Du, K.; Ivakine, Z.; Bear, C. E.
Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action 1-gen-2019 Laselva, O.; Eckford, P. D. W.; Bartlett, C.; Ouyang, H.; Guanawardena, T. N. A.; Gonska, T.; Moraes, T. J.; Bear, C. E.
Orkambi mediated rescue of mucociliary clearance in CF primary respiratory cultures is enhanced by arginine uptake, arginase inhibition and promotion of nitric oxide signalling to the CFTR channel 1-gen-2019 Wu, Y-S.; Jiang, J.; Ahmadi, S.; Lew, A.; Laselva, O.; Xia, S.; Bartlett, C.; Ip, W.; Wellhauser, L.; Ouyang, H.; Gonska, T.; Moraes, T. J.; Bear, C. E.
AN ADENOVIRAL VECTOR EXPRESSING CFTR CAN BE USED TO BENCHMARK CFTR MODULATOR RESPONSES IN PATIENT-DERIVED NASAL EPITHELIAL CELLS 1-gen-2019 Ouyang, H.; Cao, H.; Bartlett, C.; Laselva, O.; Gunawardena, T.; Duan, C.; Avolio, J.; Bear, C. E.; Gonska, T.; Hu, J.; MORAES T., J
D1152H MUTATION SHOWS A BICARBONATE BUT NOT A CHLORIDE DEFECT IN PRIMARY NASAL EPITHELIAL CELLS 1-gen-2019 Laselva, O.; Moraes, T. J.; He, G.; Barlett, C.; Szaric, S. OUYANG.; Strug, L.; Bear, C. E.; Gonska, T
Mostrati risultati da 1 a 20 di 57
Legenda icone

  •  file ad accesso aperto
  •  file disponibili sulla rete interna
  •  file disponibili agli utenti autorizzati
  •  file disponibili solo agli amministratori
  •  file sotto embargo
  •  nessun file disponibile